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Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis

Study acronym: STREAM-Line
StatusRecruiting
PhasePhase 4
Started2024-12-19
View on ClinicalTrials.gov ↗

Amendment history

2026-09-22
notable
Interventions modified
2025-05-26
minor
Study Status, Study Description, Eligibility, Contacts/Locations v2
Eligibility criteria+169 characters
[...] T and treated with any standard therapeutic anticoagulation (including LMWH dose reduction to 75% after the first month) for at least 3 months. Able and willing to provide informed [...] coagulation is contraindicated. Other indications requiring aongoing therapeutic dose of anticoagulation beyondas 3deemed monthsnecessary by treating physicians (such as atrial fibrillation, mechanical heart valve, etc.). Not on therapeutic anticoagulation at the time of enrollment (patients whose anticoagulationAnticoagulation has been permanently stopped or reduced to prophylactic dose reduced prior to enrollment [...] [...]
Study description+21 characters
The aim of the STREAM-Line Trial is to demonstrate that the STREAM-Line management strategy is safe after the initialacute treatment duration (≥ 3 months of therapeutic anticoagulation) in patients with cancer and catheter-related upper extremit [...]
Study sitescontacts updated at 1 of 1 site
2025-03-03
notable
Not Yet Recruiting→Recruiting Study Identification, Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2024-10→confirmed 2024-12-19
Study sitesdetails revised at 1 of 1 site
Study titlerevised
Secondary Prevention of VTE in Patients withWith Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis
2024-09-16
minor
Original filing
This trial seeks to evaluate a management strategy after the acute treatment duration (≥ 3 months of therapeutic anticoagulation) for patients with cancer and catheter-related upper extremity deep vein thrombosis (DVT).
Trial Details
NCT Number NCT06603870
Lead Sponsor Ottawa Hospital Research Institute
Conditions Venous Thromboembolism, Cancer, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections
Enrollment 330 participants
Start Date 2024-12-19
Primary Completion 2029-10 (estimated)
Study Completion 2029-10 (estimated)
Updated on ClinicalTrials.gov 2026-09-21