Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis

Carpometacarpal (CMC) joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women, leading to decreased muscle strength, reduced joint range of motion, and pain.The pathogenesis of thumb CMC osteoarthritis involves complex interactions between biomechanical forces, genetic predisposition, hormonal changes, repetitive microtrauma, and aging. An important factor in the progression of carpometacarpal osteoarthritis is the loss of joint stability provided by the surrounding muscles (2). The common methods for diagnosing thumb CMC OA is plain radiographs and clinical examinations. However, radiographs are unable to assess the role of surrounding structures, including muscles and ligaments. Ultrasound is a cost-effective, radiation-free, and easily applicable imaging method.

NCT Number	NCT06600464
Lead Sponsor	Fatih Sultan Mehmet Training and Research Hospital
Conditions	Osteoarthrosis, Ultrasound
Enrollment	42 participants
Start Date	2024-08-31
Primary Completion	2024-11-30 (estimated)
Study Completion	2024-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-09-19