Clinical Trial

Innovative Drug Delivery Nanophotonic Platform for Implementation of Sarcoma Therapy

Study acronym: DEEPLY
Recruiting
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Summary
DEEPLY aims to improve sarcoma therapy by the development of an innovative nanophotonic delivery approach to be applied in the future as an integrated local therapy for patients with inoperable tumors or with oligometastases. The major aim of the project is the development of innovative nanocarriers loaded with chemotherapeutic agents, whose delivery will be improved by the use of an optic fiber (optoporation). After the synthesis, and characterization of NPs, a prototype will be produced and preclinically validated on patient-derived biological material. This wide comprehensive methodological approach will ensure the obtainment of robust data to be faster exploited toward clinical applications.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-09-12.
Trial Details
NCT Number NCT06599957
Lead Sponsor Istituto Ortopedico Rizzoli
Collaborators: Università Degli Studi del Sannio Dipartimento di Ingegneria Benevento, IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori Meldola
Conditions Bone and Soft Tissue Tumors
Enrollment 30 participants
Start Date 2024-08-30
Primary Completion 2026-08-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2025-09-22