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Differential Assessment of Hypertonia

StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated October 15, 2024 (before its estimated August 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary endpoints revised (9)
    • Start date changed from estimate of Oct 2024 to Oct 9, 2024
    • Interventions: Continuous passive motion device (CPM) of ankle (Procedure) to Continuous passive motion device (CPM) of ankle - fast (Procedure), Continuous passive motion device (CPM) of ankle - slow (Procedure)
    • Secondary endpoints expanded, about 2 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements. Spasticity is characterized by a velocity-dependent increase in stretch reflexes, accompanied by exaggerated tendon responses, while rigidity is marked by consistent resistance throughout the range of motion, traditionally considered independent of stretch velocity. However, recent studies suggest that rigidity may also be influenced by stretch velocity. This study aims to investigate muscle tone by examining spasticity, rigidity, and normal muscle function through neural and biomechanical changes. Standard clinical tools, such as the Modified Ashworth Scale and Unified Parkinson's Disease Rating Scale, along with additional assessments like the Myoton and Post-Activation Depression (PAD), will be employed.
Trial Details
NCT Number NCT06596187
Lead Sponsor Chang Gung University
Conditions
(from sponsor)		 SCI - Spinal Cord Injury, PD - Parkinson's Disease
Related terms Muscle Rigidity, Muscle Spasticity, Parkinson Disease, Spinal Cord Injuries
Enrollment 45 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov