Unfolding Severe and Enduring Eating Disorders (U-SEED)

The main aim of this study is to identify biological and psychological characteristics as risk factors in individuals with severe and enduring eating disorders (SEED). Specifically, the investigators aim to: 1. in a cohort of well-diagnosed eating disorder patients from 2005 followed up in National health registers, explore risk factors at baseline (recorded 2005-2007) for development of later SEED (the registry based cohort). 2. replicate the findings in a new sample of 50 adults with ongoing SEED. Participants will be assessed diagnostically and physically, and asked to fill out questionnaires and leave blood samples (the ongoing SEED sample compared with the register based cohort). 3. in a sample of 50 adults with SEED, explore demographic, biological, clinical, and psychological factors and examine the relation between these factors and symptom severity and functional impairment (the ongoing SEED sample). 4. explore participants perspectives on their symptoms and received care (the ongoing SEED sample).

NCT Number	NCT06592963
Lead Sponsor	Uppsala University Hospital Collaborators: The Söderström König Foundation, Forte
Conditions	Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Personality Disorders
Enrollment	50 participants
Start Date	2024-06-01
Primary Completion	2026-04 (estimated)
Study Completion	2026-04 (estimated)
Updated on ClinicalTrials.gov	2024-09-19