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Corticosteroid Effect on Achalasia Variant EGJOO

StatusActive, Not Recruiting
PhaseEarly Phase 1
Started
View on ClinicalTrials.gov ↗

Record History

  1. Primary and study completion dates: Jan 2026 to Nov 2026v5
  2. Primary and study completion dates: Jun 2025 to Jan 2026v4
  3. Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 10 to confirmed 12
    • Primary and study completion dates: Mar 2025 to Jun 2025
    • Site details revised
    v3
  4. Primary and study completion dates: Dec 2024 to Mar 2025v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
EGJOO is a disorder in which the muscles of the esophagus (swallowing tube) do not function in a coordinated fashion so that swallowed material does not pass easily into the stomach. EGJOO often causes symptoms of swallowing difficulties and chest pain. The cause of EGJOO and its optimal treatment are not clear. The investigators research team suspects that EGJOO might be caused by an allergy that involves the esophagus, and that treatment with medications called corticosteroids might improve function of the esophageal muscles. The purpose of this study is to learn how corticosteroid therapy affects the muscles of the esophagus in patients suffering with EGJOO.
Trial Details
NCT Number NCT06588348
Lead Sponsor Baylor Research Institute
Conditions
(from sponsor)		 Esophagogastric Junction Outflow Obstruction
Enrollment 12 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov