Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU

There is a need to identify strategies that improve the conduct of clinical trials involving family members of intensive care unit (ICU) patients. The purpose of the present study is to evaluate recruitment and retention strategies for clinical trials involving family members of ICU patients. 4 strategies (2 recruitment and 2 retention) will be tested. Investigators will integrate the strategies into three existing studies that involve family members of ICU patients. Participants will be randomized using a 2x2 factorial design. The co-primary outcomes are recruitment percentage (participants enrolled/participants approached) and retention percentage (participants completing follow-up/participants enrolled).

NCT Number	NCT06588101
Lead Sponsor	Lady Davis Institute Collaborators: Canadian Institutes of Health Research (CIHR)
Conditions	Family Members, Recruitment, Clinical Study, Retention, Recruitment of Participants, Study Enrollment, Retention of Participants, Compensation Incentives
Enrollment	160 participants
Start Date	2024-05-01
Primary Completion	2026-04-30 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-06-04