Clinical Trial

Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell in Patients With Relapsed/Refractory Acute Leukemia

Recruiting Phase 1/2
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Summary
Acute leukemia is a malignant clonal disease of hematopoietic stem cells. At present, the treatment for acute leukemia is relatively limited, and it is still based on high-intensity chemotherapy drug therapy and hematopoietic stem cell transplantation. The prognosis of recurrent and refractory acute leukemia is poor, and there is a lack of effective treatment plan. CD7 is a specific target on the surface of T cells, and CD7 CAR-T is expected to provide a new therapeutic path for patients with relapsed refractory acute leukemia.This is an open, single-arm, single-center, prospective clinical study. The main objective of the clinical study is to evaluate the clinical safety and tolerability of CD7 CAR-T in the treatment of acute leukemia.
Trial Details
NCT Number NCT06585345
Lead Sponsor The General Hospital of Western Theater Command
Collaborators: YakeBiotech Ltd.
Conditions Acute-Leukemia
Enrollment 200 participants
Start Date 2024-02-18
Primary Completion 2027-12-31 (estimated)
Study Completion 2030-11-01 (estimated)
Updated on ClinicalTrials.gov 2024-09-05