Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients

In this study, sensitized renal transplant recipients, who present an increased risk of acute rejection, will be evaluated for the benefit of quadruple immunosuppression, adding sirolimus to the traditional scheme with tacrolimus, mycophenolate, and prednisone.

NCT Number	NCT06584773
Lead Sponsor	University of Sao Paulo General Hospital Collaborators: Carlucci G Ventura, Daniel R Salomon, Fabiana Agena, Flavio J de Paula, Francine B Lemos, Gislene Bezerra, Helcio Rodrigues, Maria da Luz Fernandes, Nelson Zocoler Galante, Noemia B de Lima, Paschoalina Romano, Patricia S Souza, Vivian Onuchic, Elias David Neto
Conditions	Disorder Related to Renal Transplantation
Enrollment	80 participants
Start Date	2015-06
Primary Completion	2024-08 (estimated)
Study Completion	2025-07 (estimated)
Updated on ClinicalTrials.gov	2024-09-05