HPP737 Substance Balance Study in Human

Main research purpose 1. Quantitative analysis of the total amount of radioactivity in excreta (urine and feces) of male healthy subjects after oral administration of \[14C\]HPP737, to obtain the cumulative excretion rate and main excretion routes of human radioactivity; 2. To identify the main metabolites in the offspring of \[14C\]HPP737 in healthy male subjects, and to determine the main biotransformation pathway and main metabolite structure; 3. To investigate the distribution of total radioactivity in whole blood and plasma and the pharmacokinetics of total plasma radioactivity in healthy male subjects after a single oral administration of \[14C\]HPP737. Participants will: 1. Take Investigational product once 2. Stay in the clinic about 7 days for checkups and tests 3. Report their symptoms

NCT Number	NCT06584058
Lead Sponsor	Newsoara Biopharma Co., Ltd.
Conditions	Psoriasis
Enrollment	8 participants
Start Date	2024-08-30
Primary Completion	2025-07-30 (estimated)
Study Completion	2025-08-30 (estimated)
Updated on ClinicalTrials.gov	2024-09-04