Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06582680 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Aging, Beta Blockers, and Thermoregulatory Responses

StatusRecruiting
PhasePhase 4
Started2024-10-04
View on ClinicalTrials.gov ↗
Record status
This record was last updated October 23, 2025 (before its estimated September 30, 2026 completion). Its status may not reflect the trial's current state.

Amendment history

2025-10-21
3 amendments v3-v5
3 re-verifications since 2024-10-18, no change to tracked fields
2024-10-10
Not Yet Recruiting→Recruiting Study Status, Study Design, Arms and Interventions, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
PhaseEarly Phase 1→Phase 4
Start dateestimated 2024-10-01→confirmed 2024-10-04
Study sites0→1
Study arms3→6
InterventionsMetoprolol (Drug), Placebo (Other), Propranolol (Drug)→Ambient Heat (Other)
2024-09-04
Study Status, Study Description, Study Design, Outcome Measures v1
PhasePhase 4→Early Phase 1
Secondary endpointsdetails revised at 1 of 2 entries
2024-08-30
Original filing
This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
Trial Details
NCT Number NCT06582680
Lead Sponsor University of Texas Southwestern Medical Center
Conditions Heat Stress, Aging
Enrollment 22 participants
Start Date 2024-10-04
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-23