Intra-Articular Catheter Total Knee Arthroplasty

This is a prospective, randomized clinical trial evaluating three groups. The groups are: Group 1 (Control): Subjects that receive only the existing standard-of-care multimodal pain management protocol and do not receive post-operative intra-articular catheter. Group 2 (Investigational Treatment/Intervention): Subjects that receive the brand 1 intra-articular catheter pump with existing standard-of-care multimodal pain management protocol in the immediate post-operative period. Group 3 (Investigational Treatment/Intervention): Subjects that receive the newer brand 2 intra-articular catheter pump with existing standard-of-care multimodal pain management protocol in the immediate post-operative period.

NCT Number	NCT06580899
Lead Sponsor	OrthoCarolina Research Institute, Inc.
Conditions	Continuous Local Infiltration Analgesia, Intra-articular Catheter, Total Knee Arthroplasty
Enrollment	65 participants
Start Date	2025-03-14
Primary Completion	2026-09-01 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-06