Clinical Trial

The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis

Study acronym: MGIA
Recruiting
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Record status
This record was last updated August 30, 2024 (before its estimated March 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?
Trial Details
NCT Number NCT06580639
Lead Sponsor Linkoeping University
Conditions Tuberculosis, Immunologic Activity Alteration
Enrollment 280 participants
Start Date 2020-08-01
Primary Completion 2025-03-01 (estimated)
Study Completion 2025-12-01 (estimated)
Updated on ClinicalTrials.gov 2024-08-30