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Effect of Esterogen Receptor Modulator on Gene in Bipolar Diseas

StatusUnknown
PhaseNot specified
Started2024-09-05
View on ClinicalTrials.gov ↗
Record status
This record was last updated August 30, 2024 (before its estimated August 2025 completion). Its status may not reflect the trial's current state.
1. Identify randomized controlled trials of tamoxifen (Estrogen Receptor modulator) in in addition to traditional treatment of bipolar disorder and synthesize the results using meta-analysis. 2. Systematically estimate the effects of Phospholipase C epsilon 1 gene (PLCE1) rs2274223and gene polymorphism on the susceptibility to treatment. 3. Study the pathway involved in the action of tamoxifen by incorporating TMX into nanoparticles and evaluating tyrosine kinase in responders WBCS culture and evaluate nanoparticle as a hope for future treatment of CNS disorders.

Amendment history 1 change detected by DataLookout

2026-09-06
minor
Trial status changed: Not Yet Recruiting → Unknown
Trial Details
NCT Number NCT06580535
Lead Sponsor Assiut University
Conditions Bipolar Disorder
Enrollment 100 participants
Start Date 2024-09-05
Primary Completion 2025-08 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2024-08-30