Intraoral Hypothermia Device for Preserving Taste During Radiation

Radiation therapy to the head and neck region is known to cause taste dysfunction. Preliminary studies showed that cooling normal structures may lower damage caused by radiation. The purpose of this research study is to see if it is feasible to use an intraoral cooling device during radiation treatments to preserve or lower the decline of taste function.

NCT Number	NCT06579248
Lead Sponsor	Henry Ford Health System
Conditions	Head and Neck Cancer, Taste Dysfunction, Radiation Therapy
Enrollment	15 participants
Start Date	2024-11-12
Primary Completion	2026-08-30 (estimated)
Study Completion	2026-08-30 (estimated)
Updated on ClinicalTrials.gov	2026-01-14