Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement Appliance

This research addresses obstructive sleep apnea syndrome (OSAS), affecting 6-12% of French adults, often treated with mandibular advancement devices (MADs). MADs may lead to occlusal modifications, causing a 50% treatment abandonment rate. The study employs surface electromyography to assess masticatory muscle activity before and during MAD use, correlating it with occlusal changes after 6 months. The primary goal is to determine dental displacement profiles post-6-month MAD treatment, providing insights for personalized care and minimizing treatment failures.

NCT Number	NCT06576310
Lead Sponsor	University Hospital, Toulouse
Conditions	Obstructive Sleep Apnea Syndrome
Enrollment	118 participants
Start Date	2025-01-06
Primary Completion	2027-10-06 (estimated)
Study Completion	2027-10-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-23