Clinical Trial

rTMS as an Intervention for Levodopa-induced Dyskinesia

Study acronym: ADAPT-LIDI
Recruiting
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Summary
The proposed study investigates the use of repetitive transcranial magnetic stimulation (rTMS) as a treatment for levodopa-induced dyskinesia (LID) in Parkinson's Disease (PD). Specifically, the study aims to determine whether patterned stimulation of the pre-supplementary motor area (pre-SMA) can delay the onset of LID after levodopa intake and reduce LID severity in PD patients. This study will provide critical insights into potential targets for rTMS treatment, optimal rTMS parameters, and the mechanisms underlying LID in Parkinson's disease.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-08-22.
Trial Details
NCT Number NCT06570824
Lead Sponsor Danish Research Centre for Magnetic Resonance
Conditions Dyskinesia, Drug-Induced, Parkinson Disease
Enrollment 68 participants
Start Date 2024-07-22
Primary Completion 2027-05-01 (estimated)
Study Completion 2027-05-01 (estimated)
Updated on ClinicalTrials.gov 2024-08-28