To Explore the Functional Connectivity Pattern of Cortical Swallowing Network in the Oral Phase of Post-stroke Dysphagia Based on Dynamic Causal Modelling

Swallowing activity in the oral phase is regulated by the cortical swallowing network, and the functional connectivity pattern of the cortical swallowing network is related to swallowing activity. The structural damage of the cortical swallowing network and abnormal activation of brain areas related to swallowing in post-stroke dysphagia affect swallowing activity. The recovery of dysphagia after stroke is related to the compensation of swallowing network in the contralateral hemisphere and different connectivity patterns of diseased brain areas, and the integrity of cortical swallowing network connectivity affects the sequence of oral swallowing activities. However, it is not clear how the functional connectivity patterns and interactions of brain regions of the cortical swallowing network related to oral swallowing activity change in patients with oral dysphagia after stroke.

NCT Number	NCT06564688
Lead Sponsor	Fujian University of Traditional Chinese Medicine Collaborators: Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science
Conditions	Dysphagia After Stroke, Cortical Swallowing Network, Functional Magnetic Resonance Imaging, Oral Phase, Dynamic Causal Modelling
Enrollment	72 participants
Start Date	2024-08-20
Primary Completion	2025-07-01 (estimated)
Study Completion	2025-07-01 (estimated)
Updated on ClinicalTrials.gov	2024-08-21