Erasme Randomized Controlled Trial Surveys Hemodynamic Excursions During Esophagectomy

In our high volume center, the majority of esophagectomy procedures are performed with minimally invasive techniques. The thoracic epidural technique remains the gold standard and homolateral paravertebral catheter is strongly recommended. The vasoplegia and sympathetic blockade due to the epidural can cause significant hypotension especially as reverse Trendelenburg position is required during surgery. The aim is to study hemodynamic changes caused by two different techniques. Previous studies found a similar pain management between both locoregional techniques, however few studies suggested less side effects in the paravertebral group during major abdominal surgeries.

NCT Number	NCT06563557
Lead Sponsor	Erasme University Hospital
Conditions	Esophagectomy, Epidural; Anesthesia, Paravertebral Anesthesia, Hemodynamic Instability
Enrollment	75 participants
Start Date	2024-08
Primary Completion	2026-08-01 (estimated)
Study Completion	2026-12-12 (estimated)
Updated on ClinicalTrials.gov	2024-08-21