Effects of Vitamin D and Prebiotic Supplementation on Glucose Control During Pregnancy

The goal of this randomized, double-blind, placebo-controlled study included pregnant women at high risk of GDM at 6-15 weeks of gestation is to investigate whether supplementation with vitamin D (1600 IU per day) or prebiotics (inulin, 10 gram per day) during pregnancy has beneficial effects on controlling blood glucose during pregnancy.

NCT Number	NCT06553729
Lead Sponsor	Huazhong University of Science and Technology
Conditions	Glucose Intolerance During Pregnancy
Enrollment	500 participants
Start Date	2025-02-24
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-16