Pilot Study on the Effectiveness of a Flexible Hydroxyapatite-Based Composite for Jaw Bone Regeneration

Following a review of the scientific literature, it was found that there are no clinical studies but only in vitro and in vivo studies, which show promising results in terms of bone formation and integration. However, it is necessary to evaluate how well the regenerated bone maintains its structural integrity over time, considering masticatory function and real-life biomechanics. Factors such as mechanical load, remodeling dynamics, and interactions with surrounding tissues could influence the long-term stability of the regenerated bone. Additionally, another important aspect to study is the potential complications and adverse effects associated with the use of the flexible HAp-based composite.

NCT Number	NCT06552715
Lead Sponsor	University of Bologna
Conditions	Bone Atrophy, Edentulism, Bone Regeneration
Enrollment	20 participants
Start Date	2024-09
Primary Completion	2025-04 (estimated)
Study Completion	2025-09 (estimated)
Updated on ClinicalTrials.gov	2024-08-14