Clinical Trial

Adaptive Dengue Antiviral Platform Trial

Study acronym: ADAPT
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
This is a randomized, open-label adaptive platform trial aiming to screen the antiviral effectiveness of the experimental drug(s) in early dengue infection * Primary objectives: * To determine the antiviral effectiveness of the experimental drug(s) in early dengue infection * To assess the safety and tolerability of the experimental drug(s) in dengue patients * Secondary objective: * To assess the effect of the experimental drug(s) in dengue patients on physiological, clinical and virological parameters
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-08-11.
Status change: Not Yet Recruiting → Recruiting 2026-04-24
Trial Details
NCT Number NCT06551844
Lead Sponsor Oxford University Clinical Research Unit, Vietnam
Collaborators: Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, University Malaya Medical Centre, Malaysia
Conditions Dengue, Antiviral Drugs
Enrollment 500 participants
Start Date 2026-04-20
Primary Completion 2029-12-31 (estimated)
Study Completion 2030-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-30