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NCT06549439 · ClinicalTrials.gov record · last posted 2026-08-21

eFLASH for Skin Lesions of Malignant Melanomas

Name: eFLASH for Skin Lesions of Malignant Melanomas — clinical trial record (NCT06549439)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: Flash-Skin I

StatusCompleted

PhaseNot applicable

SponsorUniversity of Zurich

Started2024-01-22

View on ClinicalTrials.gov ↗

from the ClinicalTrials.gov record

This prospective single center phase I trials aims to assess feasibility and safety of electron FLASH RT for treatment of melanoma skin metastases. Feasibility will be defined as FLASH delivery with an accuracy of +/-10% for each fraction, safety will be confirmed if a maximum of 2 out of 6 patients develop dose limited toxicity.

Protocol amendment history 2 changes detected by DataLookout

2026-08-22

Trial completed

2026-08-22

Enrollment reduced: 10 → 7 participants

Trial Details

NCT Number	NCT06549439
Lead Sponsor	University of Zurich Collaborators: Varian, a Siemens Healthineers Company
Conditions	Metastatic Melanoma
Enrollment	7 participants
Start Date	2024-01-22
Primary Completion	2025-05-27 (estimated)
Study Completion	2026-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-08-21