Clinical Trial

Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU

Study acronym: NOVA-AKI
Recruiting Phase 2
View on ClinicalTrials.gov →
Record status
This record was last updated April 13, 2025 (before its estimated October 10, 2025 completion). Its status may not reflect the trial's current state.
Summary
Renal dysfunction is a frequent complication in patients admitted to intensive care units (ICUs), associated with high morbidity and mortality. Current therapeutic options to prevent this condition are limited and lack robust scientific evidence. This pilot study consists of a multicenter, blinded, randomized clinical trial, unprecedented in the literature to date, aiming to fill this knowledge gap and offer new therapeutic perspectives to improve renal outcomes in critically ill patients admitted to the ICU.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-08-08; most recent amendment 2025-04-10.
Status change: Not Yet Recruiting → Recruiting 2025-04-10
Trial Details
NCT Number NCT06547892
Lead Sponsor Hospital do Coracao
Conditions Critical Illness
Enrollment 60 participants
Start Date 2025-04-10
Primary Completion 2025-10-10 (estimated)
Study Completion 2025-12-10 (estimated)
Updated on ClinicalTrials.gov 2025-04-13