Clinical Trial

Locally Optimised Contouring With AI Technology for Radiotherapy

Study acronym: LOCATOR
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated January 29, 2026 (before its estimated February 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
LOCATOR is a multicentre phase II randomised clinical trial that is looking at the process of contouring in radiation treatment for breast cancer patients. This study looks at whether contouring aided by artificial intelligence (AI) is comparable in quality to that of contouring done completely manually by a radiation oncologist. We are also looking at whether AI assisted contouring saves radiation oncologists time when compared to fully manual contouring. LOCATOR uses the LOCATOR software which is an in-house software developed locally and trained on local data.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2024-08-06; most recent amendment 2026-01-27.
Status change: Not Yet Recruiting → Recruiting 2025-03-06
Trial Details
NCT Number NCT06546592
Lead Sponsor Royal North Shore Hospital
Conditions Contouring, Segmentation, Radiation Therapy, Artificial Intelligence, Deep Learning
Enrollment 444 participants
Start Date 2025-02-11
Primary Completion 2026-02-01 (estimated)
Study Completion 2030-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-29