Clinical Trial

The Impact of Probiotics on Sperm Quality in Middle-aged Men

Completed
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Summary
The clinical trial aims to investigate the impact of probiotic strain BL21 on sperm quality among 46 middle-aged male participants. The primary objective is to validate whether probiotic strain BL21 can effectively improve sperm quality among middle-aged male participants. Initially, participants were instructed to consume the recommended amount of probiotic powder for approximately 8 weeks. At baseline, week 4, and week 8 endpoints, semen analysis, hormone level testing, serum cytokine testing were conducted on the participants, and stool samples were collected from them.
Protocol Amendment History 2 changes
critical Completed without a posted recruiting period 2026-08-04
notable Enrollment reduced: 46 -> 40 participants 2026-08-04
Trial Details
NCT Number NCT06544278
Lead Sponsor Wecare Probiotics Co., Ltd.
Conditions Semen Quality
Enrollment 40 participants
Start Date 2024-08-30
Primary Completion 2025-05-01 (estimated)
Study Completion 2025-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-07