Pilot MRI Study on Osteopathic Manipulation for Myofascial Pain Syndrome

The goal of this clinical trial is to conduct MRI studies on adults with myofascial pain syndrome (MPS) to identify important MRI biomarkers that respond to OMT (osteopathic manipulation therapy) and investigate the feasibility of implementing MRI study and OMT in this population. The main outcomes of the study include: * Determine whether biomarkers measured by MRI can differentiate normal tissues and MTrP (myofascial trigger point). * Test the responsiveness of the biomarkers identified by MRI to the proposed intervention, OMT, in patients with MPS of the upper back. Researchers will compare participants who will receive one session of OMT (Group 1 - Experimental Condition) and participants who will not receive any treatment (Group 2 - Control Condition) to see how the MRI-identified biomarkers respond to the intervention. Participants will complete the following: * Clinical screening * MRI measures * Battery of self-report surveys * Clinical/Physical Function Assessment

NCT Number	NCT06538727
Lead Sponsor	Auburn University Collaborators: Edward Via College of Osteopathic Medicine-Auburn
Conditions	Myofascial Pain Syndrome
Enrollment	20 participants
Start Date	2024-08-31
Primary Completion	2025-04-30 (estimated)
Study Completion	2025-06-30 (estimated)
Updated on ClinicalTrials.gov	2024-08-06