Clinical Trial

Dynamic Pattern of Etiology, Immunoinflammatory Factors and Their Association With Prognosis of Severe Pneumonia

Active, Not Recruiting

Record status

This record was last updated August 7, 2024 (before its estimated July 30, 2025 completion). Its status may not reflect the trial's current state.

Summary

The goal of this longitudinal observational study is to investigate the pathogen spectrum composition of severe pneumonia (SP) in different disease stages and to study the changes of immune inflammatory factors in patients with SP in different course of disease during and after the COVID-19 pandemic. The main questions it aims to answer is: What is the pathogenic profile of SP patient admitted in intensive care unit (ICU) during and after COVID-19 pandemic? What is the dynamic pattern of etiology and immunoinflammatory factors of SP progression during the period in ICU? Are those indexes mentioned above associated with the prognosis of SP?

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2024-08-03.

Trial Details

NCT Number	NCT06538441
Lead Sponsor	Shanghai General Hospital, China Collaborators: First Affiliated Hospital of Chongqing Medical University
Conditions	Severe Pneumonia
Enrollment	600 participants
Start Date	2024-08-01
Primary Completion	2025-07-30 (estimated)
Study Completion	2025-12-30 (estimated)
Updated on ClinicalTrials.gov	2024-08-07