Best Practices Fo Early Diagnosis of Cerebral Palsy

In this research, the investigators are using an implementation science approach to enhance the uptake of a clinical practice guideline for earlier diagnosis of cerebral palsy (i.e. what is being implemented) in neonatal follow-up clinics across Canada. This clinical practice guideline should be part of what neonatal follow-up specialists do in their routine clinical work with children born preterm. However, there is a wide variability in practice. The goal of this project is to harmonize practices in the neonatal follow-up community in agreement with international recommendations for earlier diagnosis of cerebral palsy. This research will measure if clinicians are truly following the clinical practice guideline. If not, implementation strategies that address barriers and leverage on facilitators will be deployed for successful uptake of the clinical practice guideline. This research will also assess whether implementation of the clinical practice guideline is associated with better patient outcomes.

NCT Number	NCT06537622
Lead Sponsor	St. Justine's Hospital Collaborators: IWK Health Centre, St. Boniface Hospital, Sunnybrook Health Sciences Centre, Montreal Children's Hospital of the MUHC, Harvard University, University of British Columbia, Queen Alexandra Centre for Children's Health, Victoria, Jewish General Hospital, CHU de Quebec-Universite Laval, BC Women's Hospital & Health Centre, Dr. Everett Chalmers Hospital, Janeway Children's Health and Rehabilitation Centre, Centre de recherche du Centre hospitalier universitaire de Sherbrooke, Horizon Health Network, Moncton hospital, Windsor Regional Hospital, Maisonneuve-Rosemont Hospital, The Hospital for Sick Children, MOUNT SINAI HOSPITAL, Health Sciences Centre, Winnipeg, Manitoba, Glenrose Foundation, Hamilton Health Sciences Centre, London Health Sciences Centre, Children's Hospital of Eastern Ontario, Kingston Health Sciences Centre, Foothills Medical Centre, Island Health, Victoria, BC, Canadian Premature babies Foundation
Conditions	Cerebral Palsy, Prematurity
Enrollment	2,000 participants
Start Date	2025-02-01
Primary Completion	2026-11-01 (estimated)
Study Completion	2028-11-01 (estimated)
Updated on ClinicalTrials.gov	2024-12-18