Clinical Trial

KetoNiFast: Cyclic Enteral Daytime Feeding With Ketogenic Nighttime Fasting

Study acronym: KetoNiFast
Recruiting
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Record status
This record was last updated August 6, 2024 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
A physiological human nutrition includes circadian feeding and nighttime fasting during sleep. There is increasing evidence, that this natural fasting episode over nighttime majorly contributes to repair processes of the human body. So far, intensive care patients are normally enterally fed continuously, so that there is no circadian nutrition and no nighttime fasting. An enteral nutrition for 12 hours followed by a fasting period of 12 hours supported by exogenous ketone salts potentially improves the reconstitution of ICU patients compared to ICU patients who are continuously enterally fed.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-07-30.
Trial Details
NCT Number NCT06535815
Lead Sponsor University Hospital of Cologne
Conditions Nutrition, Muscle Loss, Inflammatory Response
Enrollment 130 participants
Start Date 2023-09-01
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-03-01 (estimated)
Updated on ClinicalTrials.gov 2024-08-06