Optimized Strategies for Malperfusion Syndrome

An investigator-initiated, randomized, multicenter, two-arm, open-label study of consecutive patients presenting with acute type A aortic dissection (ATAAD) and malperfusion syndrome (MPS). Objectives: The present study aimed to investigate the difference in all-cause mortality after optimized treatment strategies (OTS) versus traditional treatment strategies (TTS) for ATAAD patients with MPS. Background: The mortality of ATAAD with MPS is high. However, the management strategies of MPS patients still not to be confirmed. Compare with TTS, OTS as a strategy for ATAAD patients with MPS might have be beneficial results.

NCT Number	NCT06532838
Lead Sponsor	Xiamen Cardiovascular Hospital, Xiamen University
Conditions	Aortic Dissection
Enrollment	236 participants
Start Date	2024-08-01
Primary Completion	2026-07-30 (estimated)
Study Completion	2026-10-30 (estimated)
Updated on ClinicalTrials.gov	2024-08-01