Clinical Trial

Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

Study acronym: OPUS-i
Recruiting
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Summary
This interventional trial will compare a novel prehospital stroke transport algorithm (OPUS-i) to a traditional prehospital stroke transport algorithm to improve outcomes in rural stroke patients by determining the effect of implementing a data-driven prehospital stroke algorithm on time to and endovascular therapy. The study consists of a multicenter cohort and will last 24 months but individual subject study duration is 90 days.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-07-26; most recent amendment 2026-03-10.
Status change: Not Yet Recruiting → Recruiting 2025-06-26
Trial Details
NCT Number NCT06530693
Lead Sponsor Temple University
Collaborators: Cooper University Health Care, Geisinger Medical Center, Danville, PA, Thomas Jefferson University
Conditions Stroke
Enrollment 360 participants
Start Date 2025-04-01
Primary Completion 2027-06 (estimated)
Study Completion 2027-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-12