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Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction

Study acronym: Mi-SPA
StatusRecruiting
PhaseNot applicable
Started2025-08-13
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Aug 2026 → Dec 2026
See other at-risk trials from University of Michigan

Amendment history

2026-09-16
notable
Primary completion pushed: 2026-08 → 2026-12
Completion pushed: 2026-08 → 2026-12
2025-09-04
minor
Study Status v6
Re-verified, no change to tracked fields
2025-08-12
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v5
Trial statusNot Yet Recruiting→Recruiting
Start date2025-09→2025-08-13
Study sites0→1
2025-08-03
minor
Study Status v4
Re-verified, no change to tracked fields
2025-07-28
minor
Study Status v3
Start date2025-04→2025-09
Show 2 earlier versions
2024-11-15
minor
Study Status, Oversight v2
Start date2025-01→2025-04
2024-07-30
minor
Study Status, Study Description v1
Study description+11 characters
[...] in loading from a 6-week split-belt training intervention, wethe investigators will conduct a pilot randomized clinical trial design, but [...] mill training, or 3) placebo split-belt treadmill training. OurThe primary outcome, sagittal plane knee moment, will be examined before, midway, & after the 6-weeks of training. Our otherOther outcomes, vertical ground reaction force, knee joint contac [...]
2024-07-26
minor
Original filing
The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects. Nine subjects will be randomized to 2 split-belt intervention groups (one group where early stance loading is trained and the other where midstance loading is trained) and a placebo group. The goal of this study is to explore the adaptations in knee loading from a 6-week split-belt training intervention. The investigators' main question for this aim is: 1. Does knee loading, measured by the sagittal plane knee moment, change to a greater extent in the split-belt treadmill training groups compared to the placebo group? 2. Are there differences in training-related knee loading changes between individuals trained in the early stance vs. midstance loading split-belt training?
Trial Details
NCT Number NCT06529692
Lead Sponsor University of Michigan
Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions ACL, Anterior Cruciate Ligament, ACL Injury
Enrollment 9 participants
Start Date 2025-08-13
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-09-15