Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women with Pyelonephritis

The goal of this clinical trial is to compare rates of cure in pregnant women with pyelonephritis. The main question aims to answer: Can we treat pyelonephritis in pregnancy with oral cefuroxime alone? Pregnant women with pyelonephritis treated with intravenous cefuroxime will be the comparator. Participants will be asked to accept participation in the study and will be randomly allocated to one of the two arms: * Intravenous cefuroxime 750 mg every 8 hours + oral placebo every 12 hours * Oral cefuroxime 500 mg every 12 hours + intravenous saline solution every 8 hours

NCT Number	NCT06527560
Lead Sponsor	Hospital de Clinicas de Porto Alegre
Conditions	Pyelonephritis in Pregnancy
Enrollment	100 participants
Start Date	2024-09-09
Primary Completion	2027-12-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-09-19