Withholding of Life-sustaining Treatment and Quality of Life After Severe Acute Brain Injury: Qualitative Analysis and Ethical Issues

Withdrawal of life-sustaining treatment affects 10-15% of ICU patients, including those with severe acute brain injury, whose care appears futile in terms of prognosis based on clinical and paraclinical data, expected quality of life, patient preferences, age, or reduced quality of life. There are few studies on withholding treatment compared with withdrawing treatment, and even fewer on survivors after a decision to withhold treatment. Quality of life is defined by WHO as "an individual's perception of his or her position in life in the context of the culture and value systems in which he or she lives and in relation to his or her goals, expectations, standards and concerns". The relationship between quality of life and neurological outcome after severe acute brain injury is controversial and therefore difficult to predict. That's why the investigators question the legitimacy of making decisions to withhold treatment from patients with severe acute brain injury based on their expected quality of life, when this prediction is uncertain.

NCT Number	NCT06523127
Lead Sponsor	Centre Hospitalier Universitaire de Saint Etienne
Conditions	Quality of Life, Brain Injuries, Post ICU
Enrollment	14 participants
Start Date	2024-06-03
Primary Completion	2024-09 (estimated)
Study Completion	2024-09 (estimated)
Updated on ClinicalTrials.gov	2024-07-26