Tranexamic Acid for Anaemia Trial

Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods. Anaemia can womwn make feel tired, weak, dizzy and out of breath. It can also make it harder to study, work or look after their family. If woman become pregnant with anaemia, it can cause problems for both mother and baby, such as early birth or heavy bleeding when giving birth. It is best to treat anaemia in young women well before they get pregnant. Doctors treat anaemia with iron and vitamins. But some people get side effects when taking iron tablets and so they stop taking them. Tranexamic acid (TXA) is a medicine used to treat heavy periods. The investigators of this study would like to find out if taking TXA with the usual iron and vitamin supplements is better at treating anaemia than taking iron and vitamin supplements alone. (Lay Summary)

NCT Number	NCT06519422
Lead Sponsor	London School of Hygiene and Tropical Medicine Collaborators: University of Dar es Salaam, Tanzania (Mbeya College of Health and Allied Sciences), Coefficient Giving (Formerly Open Philanthropy), Versailles Saint-Quentin-en-Yvelines University, Shifa Tameer-e-Millat University, University College Hospital, Ibadan, The Jon Moulton Charity Trust, University of Edinburgh
Conditions	Anaemia
Enrollment	4,000 participants
Start Date	2026-08
Primary Completion	2028-08 (estimated)
Study Completion	2028-09 (estimated)
Updated on ClinicalTrials.gov	2026-08-13