Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain

The goal of this clinical trial is to evaluate whether performing genicular nerve ablation (GNA) before geniculate artery embolization (GAE) improves pain relief and knee function in patients with chronic knee pain. The main questions it aims to answer are: * Does performing GNA prior to GAE enhance pain relief, as measured by the Visual Analog Scale (VAS), at 3 months post-procedure? * Does the sequential approach improve knee function as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)? Study investigators will compare two groups to see if the sequential approach (GNA followed by GAE) provides better outcomes compared to GAE alone. Participants will: * Undergo either sequential GNA followed by GAE or GAE alone * Have their knee pain and function assessed at baseline, 1 month, 3 months, and 6 months post-procedure * Complete a structured patient satisfaction questionnaire (PSQ) at 3 months post-procedure * Be monitored for procedure-related adverse events up to 6 months post-procedure,

NCT Number	NCT06514755
Lead Sponsor	Zagazig University
Conditions	Chronic Knee Pain, Osteoarthritis
Enrollment	60 participants
Start Date	2024-09-29
Primary Completion	2025-03-30 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2024-10-01