Activity of Bioactive Natural Compounds as Potential Agonists of GLP1R

The goal of this clinical trial is to learn if natural bioactive compound jubenine works to reduce appetite and to favour weight loss. It will also learn about the safety of natural bioactive compound jubenine. The main questions it aims to answer are: Does natural bioactive compound jubenine reduce the hunger perception or increase the satiety perception, and, consequently, reduce food intake? What medical problems do participants have when taking natural bioactive compound jubenine? Researchers will compare natural bioactive compound jubenine to a placebo (a look-alike substance that contains no drug) to see if natural bioactive compound jubenine works to reduce food intake for obesity treatment. Participants will: Take natural bioactive compound jubenine or a placebo three times every day for 3 months. Visit the clinic once every 1 week for checkups and tests. Keep a diary of their symptoms and potenital adverse effects.

NCT Number	NCT06513715
Lead Sponsor	Universidad Católica San Antonio de Murcia
Conditions	Obesity, Overweight
Enrollment	100 participants
Start Date	2024-01-09
Primary Completion	2026-01-31 (estimated)
Study Completion	2026-07-01 (estimated)
Updated on ClinicalTrials.gov	2024-07-22