Evaluate the Efficacy and Safety of Radiotherapy Combined With Ripretinib in the Treatment of Unresectable Advanced GIST

The goal of this prospective study is to learn whether there is a synergistic effect when radiotherapy is combined with ripretinib in the treatment of patients with unresectable advanced GIST. It will also learn about the safety of this regimen.The main questions it aim to answer is: Dose radiotherapy combined with ripretinib prolong the time to disease progression for patients with advanced GIST?

NCT Number	NCT06507683
Lead Sponsor	First Affiliated Hospital of Chongqing Medical University Collaborators: Peking University Cancer Hospital & Institute
Conditions	Gastrointestinal Stromal Tumors
Enrollment	32 participants
Start Date	2024-05-28
Primary Completion	2027-07 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2024-07-18