Oxidative-reductive Processes and the Degree of Inflammation in Saliva With Conventional Brackets and Clear Aligners

The purpose of this prospective observational study is to evaluate the differences in oxidative-reductive processes and the degree of inflammation in saliva during treatment with conventional brackets and clear aligners. The evaluation will be performed by determining the salivary values of Total oxidant status (TOS), total antioxidant status (TAS) and 8-hidroxy-2'-deoxyguanosine (8OHdG).

NCT Number	NCT06507592
Lead Sponsor	University of Campania Luigi Vanvitelli
Conditions	Inflammation, Oxidative Stress, TNF-α
Enrollment	26 participants
Start Date	2023-01-27
Primary Completion	2024-05-31 (estimated)
Study Completion	2024-12-21 (estimated)
Updated on ClinicalTrials.gov	2024-07-18