Clinical Trial

Low-Dose Ketamine Infusion During Burn Wound Care

Study acronym: IMPROVE
Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated December 13, 2024 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-07-11.
Trial Details
NCT Number NCT06506565
Lead Sponsor University of Tennessee
Conditions Burn, Pain, Dissociation, Opioid
Enrollment 140 participants
Start Date 2024-07-08
Primary Completion 2025-12 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2024-12-13