Clinical Trial

SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom

Unknown
View on ClinicalTrials.gov →
Record status
This record was last updated July 16, 2024 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The aims of this prospective natural history study are to define the seizure, neuro-developmental, and behavioural characteristics of SCN1A-related epilepsies/Dravet syndrome in children and adults longitudinally over a period of three years. In addition, this study will compare missense and truncating genotypes in terms of i) rates of change of countable convulsive seizures per month and ii) neurodevelopmental outcome and trajectories.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Unknown 2026-08-02
Trial Details
NCT Number NCT06504511
Lead Sponsor NHS Greater Glasgow and Clyde
Conditions SCN1A, Dravet Syndrome, Epilepsy
Enrollment 400 participants
Start Date 2023-11-20
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-06-01 (estimated)
Updated on ClinicalTrials.gov 2024-07-16