Clinical Trial

Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The proposed hybrid effectiveness-implementation study will systematically adapt the Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (IMARA) curriculum that was previously adapted for South Africa (IMARA-SA) to use in Zambia (will be renamed Zambian Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (ZAIMARA) and evaluate the impact of ZAIMARA on improving adolescent girls and young women HIV testing, HIV and STI incidence, PrEP uptake and sexual risk behaviour. The study will also assess the impact of monthly mental health screening with referral versus a monthly nutrition and exercise screening on peer leaders job retention. We will also examine implementation factors and outcomes associated with ZAIMARA across five sites.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2024-07-10; most recent amendment 2026-06-17.
Status change: Recruiting → Active, Not Recruiting 2026-06-17
Status change: Not Yet Recruiting → Recruiting 2025-08-19
Trial Details
NCT Number NCT06503666
Lead Sponsor Centre for Infectious Disease Research in Zambia
Collaborators: University of Illinois at Chicago, University of Alabama at Birmingham
Conditions HIV Infections, Sexually Transmitted Diseases
Enrollment 1,200 participants
Start Date 2025-04-07
Primary Completion 2026-12-01 (estimated)
Study Completion 2028-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-22