Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System

The goal of this clinical trial is to investigate the possible role of levonorgestrel intrauterine system use(LIU) in the pathogenesis of temporomandibular joint disorder (TMD). In this clinical trial, levonorgestrel intrauterine system patients (n=30) aged 25-50 and control group patients (n=30) with the same demographics and age range are used. The main questions it aims to answer are: To compare the frequency of temporomandibular dysfunction in women using the levonorgestrel intrauterine system with the control group of the same demographic and age range. The levonorgestrel intrauterine system use group consisted of 50 women who had previously a mirena implanted by a gynecologist at least 3 months ago due to menstrual bleeding and pelvic pain. The control group included 50 randomised healthy women who had regular menstrual cycles and were not taking any medication.

NCT Number	NCT06500390
Lead Sponsor	Marmara University
Conditions	Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders, Temporomandibular Disorder
Enrollment	100 participants
Start Date	2024-01-15
Primary Completion	2024-04-15 (estimated)
Study Completion	2024-12-15 (estimated)
Updated on ClinicalTrials.gov	2024-11-25