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A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis

StatusRecruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated October 17, 2024 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Interventions: Cyclophosphamid (Drug), Methotrexate (Drug), Prednisone (Drug), Rituximab (Drug), Tocilizumab (Drug), Tofacitinib (Drug) to Adalimumab (Drug), Methotrexate (Drug), Prednisone (Drug), Tocilizumab (Drug), Tofacitinib (Drug)
    • Eligibility criteria expanded, about 101 words
    • Study description expanded, about 80 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study aimed to compare the efficacy and safety of a precision treatment regimen based on clinical-molecular phenotypes with a conventional treatment regimen in the treatment of patients with active Takayasu's arteritis based on a randomized, controlled, open-label, multicenter study.
Trial Details
NCT Number NCT06498089
Lead Sponsor Shanghai Zhongshan Hospital
Conditions
(from sponsor)		 Takayasu Arteritis
Related terms Takayasu Arteritis
Enrollment 124 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov