Exhaustive French National Registry of AF Ablation Using Pentaspline Pulsed Field Ablation Catheter

Pulsed field ablation (PFA) is a nonthermal ablative modality using a strong electrical field created around a dedicated catheter to produce pores in the cellular membrane. As the amount of energy required to produce electroporation is highly tissue dependent, the atrial myocardium can be specifically targeted while sparing adjacent tissues. This new ablation modality could increase the safety of pulmonary vein isolation (PVI) procedures compared to PVI using thermal energies. The investigators aim to provide the first exhaustive Nationwide registry using the pentaspline PFA catheter to treat atrial fibrillation patients.

NCT Number	NCT06497933
Lead Sponsor	University Hospital, Rouen
Conditions	Atrial Fibrillation
Enrollment	5,223 participants
Start Date	2021-03-01
Primary Completion	2023-03-01 (estimated)
Study Completion	2026-03-01 (estimated)
Updated on ClinicalTrials.gov	2024-07-19