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ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 7 months later Nov 30, 2026 → Jun 30, 2027
See other at-risk trials from University of Chile

Record History

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  1. Notable Primary and study completion pushed from Nov 30, 2026 to Jun 30, 2027
    • Eligibility criteria shortened, about 14 words
  2. Notable Trial status: Not Yet Recruiting to Recruitingv3 Show 6 more changesShow less
    • Primary and study completion dates: May 31, 2025 to Nov 30, 2026
    • Start date changed from estimate of Aug 1, 2024 to Mar 1, 2025
    • Primary endpoints: 3 to 2
    • Study sites: 0 to 4
    • Eligibility criteria revised
    • Secondary endpoints: 9 to 6
  3. Minor Re-verified, no change to tracked fieldsv2
  4. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
3,531 trials monitored
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Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis for recovery has improved; however, there is still a limit that no therapy has been able to overcome, related to spontaneous recovery as part of the natural evolution of the pathophysiological process, rather than with the contribution of rehabilitation. Additionally, existing therapies show partial effectiveness on the recovery of UE function, but do not avoid the use of compensatory strategies or alternatives to normal movement. Given this situation, there is an active search for new therapeutic approaches. In this clinical trial the investigators propose a rehabilitation paradigm that promotes the recovery of control of specific planes of movement through the selective restriction of degrees of freedom, simplifying control demands. The investigators sought to test the hypothesis that people with stroke in the early subacute stage and who present alterations in the movement of the upper extremity, a rehabilitation protocol that reduces the degrees of freedom of the UE and trunk, enables greater recovery of the movement of the UE and less use of compensatory movements compared to a protocol without DoF control. The general objective is to demonstrate the effect of training with restriction of the degrees of freedom of UE and trunk, mediated by an exoskeleton and videogames, on the control of the UE.
Trial Details
NCT Number NCT06496529
Lead Sponsor University of Chile
Collaborators: Agencia Nacional de Investigación y Desarrollo
Conditions
(from sponsor)
Stroke
Related terms Stroke
Enrollment 44 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov