Clinical Trial

PIEB Compared With CEI on Breakthrough Pain in Nulliparous Women

Recruiting
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Summary
The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in nulliparous women compared to continuous epidural infusion. Nulliparous women will randomly be divided during labor into two groups; study group will receive mix of Bupivacaine and fentanyl once (bolus) every 60 minutes; the control group will receive continuously the same dose during an hour, until delivery.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2024-07-02; most recent amendment 2026-04-07.
Status change: Not Yet Recruiting → Recruiting 2024-09-25
Trial Details
NCT Number NCT06494280
Lead Sponsor Holy Family Hospital, Nazareth, Israel
Conditions Breakthrough Pain
Enrollment 240 participants
Start Date 2024-09-10
Primary Completion 2026-11 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-13