Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controlled Trial

To evaluate the efficacy of systematically offering newly diagnosed ALD patients to AUD treatment, in the hepatology clinic, on alcohol abstinence after 6 months. The investigators will conduct a randomized controlled superiority trial with parallel group design, hypothesis blinding and blinded outcome assessment comparing A) a offer to specialized AUD treatment (intervention) and B) standard care (control). Existing observational cohort ALD members will contribute to the control group in addition to the randomized controls. The primary outcome is abstinence throughout the last 30 days assessed 6 months after randomization.

NCT Number	NCT06493773
Lead Sponsor	Zealand University Hospital Collaborators: Center for Clinical Research and Prevention, Novavi Outpatient Clinics
Conditions	Liver Diseases, Alcoholic, Alcohol Use Disorder, Treatment Adherence, Alcoholism, Liver Disease; Alcohol-Related
Enrollment	221 participants
Start Date	2025-11-15
Primary Completion	2029-04-01 (estimated)
Study Completion	2029-04-01 (estimated)
Updated on ClinicalTrials.gov	2025-11-18