Chitosan Phonophresis on Cervical IN Smartphone Addicted Users

A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflammation and provides an analgesic effect.

NCT Number	NCT06491992
Lead Sponsor	October 6 University
Conditions	Cervical Pain
Enrollment	30 participants
Start Date	2024-07-01
Primary Completion	2024-09-30 (estimated)
Study Completion	2024-10-15 (estimated)
Updated on ClinicalTrials.gov	2024-07-09